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Hunter Moseley PhD ude.yku@yelesom.retnuh
ORCID: 0000-0003-3995-5368 |
Specializations
- Systems biology
- Translational bioinformatics
- Biophysical informatics
Research areas
Academic appointment
- Associate Professor, Department of Molecular and Cellular Biochemistry
Administrative appointment
- Associate Director, Institute for Biomedical Informatics
- Informatics Core Director, Resource Center for Stable Isotope-Resolved Metabolomics
Education
- PhD in Biochemistry and Molecular Genetics; University of Alabama at Birmingham; Birmingham, AL
- BA in Chemistry, Computer Science, and Mathematics triple major, Biology minor; Huntingdon College; Montgomery, AL
Biography
Hunter Moseley’s research interests include developing computational methods, tools, and models for analyzing and interpreting many types of biological and biophysical data that enable new understanding of biological systems and related disease processes. His formal education spans multiple disciplines including chemistry, mathematics, computer science, and biochemistry. He has over 25 years of experience in bioinformatics research, particularly in the development of automated analyses of nuclear magnetic resonance (NMR) and mass spectrometry (MS) data. This includes extensive expertise in algorithm development, mathematical modeling, and systems biochemistry. He also has unique educational and research experiences that allow him to work across computational, mathematical, and biological fields, facilitating and leading collaborations between computational, statistical, and biological scientists. He is the Informatics Core Director within the NIH Common Fund-supported Resource Center for Stable Isotope Resolved Metabolomics (RC-SIRM) at the University of Kentucky (UK). His multidisciplinary lab is actively developing methods to analyze and integrate metabolomics data with other omics-level datasets for systems-level analyses that can extract mechanistic information on specific human diseases which will translate into clinical practice.
Awards
- 2015, UK College of Education Teacher Who Made A Difference Honoree
- 2012, Kentucky Academy of Science Outstanding Early Career Award
- 2011, University of Louisville Faculty Favorite Award (nominated by students for excellence in teaching)
- 2010, Kentuckiana Metroversity Award for Instructional Development (regional multi-university award)
- 2008, University of Louisville Faculty Learning Community on Critical Thinking
Courses
- BCH 401G Honors, Fundamentals of Biochemistry
- IBS 611, Practical Statistics
Projects
Publications and other works
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- journal article | 2020
- A chemical interpretation of protein electron density maps in the worldwide protein data bank
- PloS one
-
- journal article | 2020
- Atom Identifiers Generated by a Neighborhood-Specific Graph Coloring Method Enable Compound Harmonization across Metabolic Databases
- Metabolites
-
- journal article | 2020
- Deriving Lipid Classification Based on Molecular Formulas
- Metabolites
-
- journal article | 2020
- GOcats: A tool for categorizing Gene Ontology into subgraphs of user-defined concepts
- PloS one
-
- journal article | 2020
- Loss of CLN3, the gene mutated in juvenile neuronal ceroid lipofuscinosis, leads to metabolic impairment and autophagy induction in retinal pigment epithelium
- Biochimica et biophysica acta. Molecular basis of disease
-
- journal article | 2020
- MEScan: a powerful statistical framework for Genome-Scale mutual exclusivity analysis of cancer mutations
- Bioinformatics (Oxford, England)
-
- journal article | 2020
- Robust Moiety Model Selection Using Mass Spectrometry Measured Isotopologues
- Metabolites
-
- journal article | 2020
- SSIF: Subsumption-based Sub-term Inference Framework to audit Gene Ontology
- Bioinformatics (Oxford, England)
-
- journal article | 2019
- Advances in gene ontology utilization improve statistical power of annotation enrichment
- PloS one